Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma.

EBioMedicine · 2020 · PMC7475111 · PMID 32861198

Europe PMC DOI

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highly significantno p-value reported

2 B for bead 15 where this correlation was highly significant. 3.2 Correlation of LAG3 methylation and mRNA expression with immune cell infiltrates Considering the function of LAG3 as an inhibitory checkpoint receptor known to be expressed on leukocytes, we assumed expression of LAG3 to correlate with levels of tumor infiltrating immune cells.

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