Barely Significant
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Response to SSRI intervention and amygdala activity during self-referential processing in major depressive disorder.

Neuroimage Clin · 2020 · PMC7476063 · PMID 32871385

Europe PMCDOI
1
hedged sentence
0.0510
closest p · 1.0× alpha
0.0510
boldest claim

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marginally significantp = 0.051so close (0.05 < p ≤ 0.1)
Paired samples t-tests revealed that while neither the HC nor the non-responders had a significant change in amygdala activity to words of either valence following SSRI intervention (ts < 0.38, ps > 0.71, ds < 0.34), responders had a significant increase in amygdala activity to positive words (t(10) = 5.15, p < 0.001, d = 3.2) and a marginally significant decrease to negative words (t(10) = 2.19, p = 0.051, d = 0.93).

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