Interestingly, although measured salivary cortisol and cortisone levels are free (nonbound) levels, one study in healthy volunteers showed a nonsignificant trend of higher salivary cortisol and cortisone levels in women with higher estrogen levels (pregnant women or those taking oral contraceptives) [ 4 ].
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Salivary Cortisol in the Diagnosis of Cushing Syndrome, Always More Than One!
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