High-Throughput Metabolomics Method for Discovering Metabolic Biomarkers and Pathways to Reveal Effects and Molecular Mechanism of Ethanol Extract From <i>Epimedium</i> Against Osteoporosis.

Front Pharmacol · 2020 · PMC7481463 · PMID 32973531

Europe PMC DOI

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extremely significantp<0.01actually significant

After treatment with different doses of Ext-epi, the BMC and BMD of the femur are significantly higher than model rats, among which the ZL-IL group has an extremely significant difference (p<0.01), the contents of OC, TNF-α, and TRAP in the serum of rats in the model group are higher than sham-operation group, and the contents of E2 decreased significantly (p<0.01).

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