A high neutrophil-lymphocyte ratio and platelet-lymphocyte ratio are associated with a worse outcome in inflammatory breast cancer.

Breast · 2020 · PMC7481565 · PMID 32890963

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0700

boldest claim

The sentences

borderline significantP = .060so close (0.05 < p ≤ 0.1)

In a multivariate model including cN-stage ( P = NS) and HR status (HR: 0.42, 95%CI: 0.22–0.79, P = .007), the NLR remained borderline significant (HR: 0.51, 95%CI: 0.26–1.02, P = .060). 4 Discussion In this study, we investigated commonly used peripheral inflammation markers (NLR, PLR and LMR) in a cohort of 127 IBC patients (of which 34 patients had metastatic disease).

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borderline significanceP = .07so close (0.05 < p ≤ 0.1)

When using the median of 2.738 as a cut-off between high and low NLR, the survival difference reached only borderline significance (HR: 0.65; 95% CI: 0.41–1.03; P = .07) ( Table S7 ).

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