Regulatory effects of the Uty/Ddx3y locus on neighboring chromosome Y genes and autosomal mRNA transcripts in adult mouse non-reproductive cells.

With the H3K27ac ChIP-Seq, the regions showing the most highly significant differences in left ventricular chromatin from WT and Uty GT mice concerned two MSY peaks, i.e. one in the first exon region of Uty (FDR = 1.3E − 27) and one in the first intron region of Ddx3y (FDR = 1.2E − 27) (Fig. 3 ).

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