an increasing trendp < 0.001
The ITS analysis showed an increasing trend in NLHC uptake (9.25, 8.98–9.52, p < 0.001) pre-P4P, a step change of −22.9 (−24.5 to −21.2, p < 0.001), and a sustained decrease in trend of −7.10 (−7.88 to −6.33, p < 0.001) in NLHC uptake overall ( Table 2 ).