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A computational framework for modeling and studying pertussis epidemiology and vaccination.

BMC Bioinformatics · 2020 · PMC7492136 · PMID 32938370

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an increasing trendno p-value reported
Moreover, the European Centre for Disease Prevention and Control (ECDC) in its annual 2017 report [ 15 ] highlighted an increasing trend of Pertussis cases in EU, probably due to the decrease in vaccine effectiveness over time and pathogen adaptation [ 14 , 16 , 17 ].

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