NF-κB inhibition prevents acute shear stress-induced inflammation in the saphenous vein graft endothelium.

Interestingly, gene set enrichment analysis between the two acute groups (high and low shear) revealed highly significant enrichment of biological process GO-terms involved in the inflammatory response, cytokine-mediated signalling and neutrophil activity, in grafts exposed to high shear, but not low (Supplementary Figure 8 B,C).

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