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Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017.

J Epidemiol · 2020 · PMC7492704 · PMID 31548437

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an increasing trendno p-value reported
9 , 10 Actually, the incidence of KD has recently shown an increasing trend in many regions, especially in Asian countries. 3 – 5 , 7 In Shanghai, a well-developed city in China, the incidence of KD increased from 16.8 to 55.5 per 100,000 children <5 years old from 1998 through 2012. 6 , 11 Coronary artery lesions (CAL) are still the main factors affecting the long-term prognosis and mortality of KD.

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a decreasing trendno p-value reported
Fortunately, the proportion of CAL among KD patients showed a decreasing trend with the increasing administration of large dose of intravenous immunoglobulin (IVIG). 3 , 4 , 8 , 9 In Shanghai, the proportion of CAL decreased from 19.8% to 15.9% from 1998 through 2012. 6 , 11 We have conducted three epidemiologic surveys of KD in Shanghai since 1998 (once every 5 years).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.