Effect of Triptolide on Temporal Expression of Cell Cycle Regulators During Cardiac Hypertrophy.

Front Pharmacol · 2020 · PMC7498627 · PMID 33013405

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an increasing trendno p-value reported

Further studies showed that the mRNA expression of β-MHC was lowest at day 1, followed by an increasing trend ( Figure 4B ).

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a decreasing trendno p-value reported

The mRNA expression levels of p21 and p27 increased soon after stimulation, and thereafter, mRNA expression levels of all cell cycle factors showed a decreasing trend and reached their lowest levels in 1–3 h, except for cyclin-dependent kinase 1 (CDK1) and CDK4 mRNA.

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