Vitamin D Receptor Protects Against Dysbiosis and Tumorigenesis via the JAK/STAT Pathway in Intestine.

6 The VDR regulation of gut microbiome in human and animal studies represents a newly identified and highly significant activity for VDR. 7 , 8 , 9 Human Vdr gene variation shapes the gut microbiome and Vdr deletion leads to dysbiosis. 8 Our study on VDR and bacteria establishes a microorganism-induced program of epithelial cell homeostasis and repair in the intestine. 10 Dysregulation of bacterial–host interaction

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