A Physiologically-Based Pharmacokinetic Model for the Prediction of "Half-Life Extension" and "Catch and Release" Monoclonal Antibody Pharmacokinetics.

CPT Pharmacometrics Syst Pharmacol · 2020 · PMC7499188 · PMID 32697437

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a slight trendno p-value reported

There is a slight trend toward overprediction and underprediction of t 1/2 in Tg32 mouse and human, respectively ( Figure 1 ).

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