A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity.

Nat Commun · 2020 · PMC7499300 · PMID 32943637

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an increasing trendno p-value reported

There was an increasing trend in seroincidence with age during an outbreak for HCoV-229E in Tecumseh, Michigan 118 , but a similar analysis of HCoV-OC43 seroincidence in the same outbreak showed no such increase 126 .

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