Association of APOE e2 genotype with Alzheimer's and non-Alzheimer's neurodegenerative pathologies.

Nat Commun · 2020 · PMC7501268 · PMID 32948752

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highly significantno p-value reported

For AD-related pathologies of amyloid plaques and Braak stage, e2 had large and highly significant protective effects contrasted with e3/e3 and e4 carriers with odds ratios of about 0.50 for e3 contrasts and 0.10 for e4 contrasts.

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