Rapid reduction of malaria transmission following the introduction of indoor residual spraying in previously unsprayed districts: an observational analysis of Mopti Region, Mali, in 2017.

The opposite effect was observed in Ségou Region, where peak incidence at those HFs where IRS was withdrawn after the 2016 campaign (n = 19) increased by an average of 106% (CI 95 63–150%) from year to year, also a highly significant difference-in-differences compared to the standard no-IRS HFs (p < 0.0001) (Fig. 3 ).

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