Barely Significant
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Health outcomes and costs in patients with osteoarthritis and chronic pain treated with opioids in Spain: the OPIOIDS real-world study.

Ther Adv Musculoskelet Dis · 2020 · PMC7502862 · PMID 32994809

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highly significantno p-value reported
In both cases, there was a highly significant linear growth: R 2 = 0.963 for weak opioids and R 2 = 0.991 for strong opioids.

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