Current Methods of Magnetic Resonance for Noninvasive Assessment of Molecular Aspects of Pathoetiology in Multiple Sclerosis.

The highest potential of this technique is in the long-term monitoring of the disturbed microenvironment of MS lesions and veins, showing an increasing trend in the accumulation of iron deposits in these areas [ 28 ]. - Cerebral perfusion MRI provides information on capillary microcirculation in the tissue based on generating a blood flow contrast between multiple images by using a wide variety of blood-labeling methods such as exogenous tracers (Gd-contrast agent) or water protons from the arterial blood (arterial spin labeling) [ 32 ].

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