Biased versus Partial Agonism in the Search for Safer Opioid Analgesics.

Molecules · 2020 · PMC7504468 · PMID 32854452

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highly significantno p-value reported

Moreover, a detailed analysis of morphine and fentanyl ED 50 values for analgesia versus their ED 50 for respiratory depression and constipation yielded highly significant correlation coefficients.

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