In addition, with doxycycline treatment, there was an increasing trend in levels of chondrogenic inducer (i.e., sox‐9 and transforming growth factor β receptor II), and chondrogenic genes (i.e., aggrecan and collagen II) over chondrogenic culture time (Lee et al., 2013 ).
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Doxycycline preserves chondrocyte viability and function in human and calf articular cartilage ex vivo.
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