Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants.

Bone Rep · 2020 · PMC7509196 · PMID 32995386

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highly significantno p-value reported

Our results showing suppressed level of TIMP-2 and a highly significant elevation of TIMP-3 would support such role, whereas TIMP-1, which did not differ from healthy, appears only to have a subordinate role during remodeling of the hypertrophic cartilage.

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