Mean and variability of annual haemoglobin A1c are associated with high-risk peripheral artery disease.

The prevalence of high-risk PAD showed a positive trend from the lower mean with lower SD group to the higher mean with higher SD group (16.2% in the lower mean with lower SD group, 15.5% in the higher mean with lower SD group, 18.4% in the lower mean with higher SD group and 22.0% in the higher mean with higher SD group; p < 0.001).

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To understand the relationship between the HbA1c trajectories and high-risk PAD in patients with HbA1c ⩾7.4%, 502 patients with a low SD of annual HbA1c were grouped into the stable group, 1026 patients with a decreasing trend of annual HbA1c were grouped into the improving group and 544 patients with an increasing trend of annual HbA1c were grouped into the worsening group.

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