Osmolytes dynamically regulate mutant Huntingtin aggregation and CREB function in Huntington's disease cell models.

S2B.) Sorbitol and trehalose gave dose-dependent induction of HSP70 expression with the increase being highly significant (p < 0.001) at the 150 mM osmolyte concentration (Fig. 2 A,B).

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Probability of difference P > 0.05 is defined as not significant (ns), between 0.01 and 0.05 is significant (*), < 0.01 is very significant (**), and < 0.001 is extremely significant (***).

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