almost significantp-value = 0.0573
We observed an almost significant (p-value = 0.0573) positive correlation (Spearman's rank correlation coefficient r = 0.3635) between HDI and the frequency of A subtype and a significant (p-value = 0.0122) negative correlation (Spearman's rank correlation coefficient r = − 0.4669) between HDI and the frequency of D subtype (Fig. 1 S of supplementary material).