Lymphocytic infiltration in stage II microsatellite stable colorectal tumors: A retrospective prognosis biomarker analysis.

PLoS Med · 2020 · PMC7514069 · PMID 32970670

Europe PMC DOI

hedged sentences

0.0420

closest p · 0.8× alpha

0.0420

boldest claim

The sentences

borderline significantP = 0.042actually significant

A borderline significant prognostic association was confirmed in this dataset among all tumors, including those that were MSI (HR = 0.56, 95% CI 0.31–1.00, P = 0.042, Fig 6C ).

also in 11,409 other papers

highly significantno p-value reported

Interestingly, the well-described PD1 pathway that is a known immunotherapy target in advanced disease appears as highly significant in our early stage dataset, too.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.