Metabolic dysfunction and early-onset colorectal cancer - how macrophages build the bridge.

The recent analysis of Hussan et al showed an increasing trend in CRC among young patients with obesity, that could not be demonstrated in other types of gastrointestinal cancer.( 8 ) Focusing on the age of diagnosis in patients with CRC, an increased cancer risk was shown after a diagnosis of type 2 diabetes, especially in men younger than 55 years.( 31 ) A r

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