Evaluating the Performance of p16^INK4a Immunocytochemistry in Cervical Cancer Screening.

p16 Staining, HPV Results by Different Cytologic and Pathologic Grades The rates of p16 staining positivity, HPV positivity, and HPV16/18 positivity each showed an increasing trend with the severity of pathologic grades ( P trend <0.0001), as well as with the severity of LBC abnormality ( P trend <0.0001) ( Table 1 ).

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