Moderately high folate level may offset the effects of aberrant DNA methylation of P16 and P53 genes in esophageal squamous cell carcinoma and precancerous lesions.

Genes Nutr · 2020 · PMC7526188 · PMID 32993492

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a decreasing trendno p-value reported

An increased serum folate level was also related to a decreasing trend of EPL and ESCC risks when p16 or p53 methylation occurred.

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