Cytoprotective effects of fermented oyster extracts against oxidative stress-induced DNA damage and apoptosis through activation of the Nrf2/HO-1 signaling pathway in MC3T3-E1 osteoblasts.

Furthermore, in the LDH assay, cells exposed to H 2 O 2 showed a marked increase in LDH release, while there was a decreasing trend in FO-pretreated cells, as for NAC-pretreated cells (Figure 2D (Fig. 2) ), indicating that FO strongly protected against MC3T3-E1 cell apoptosis by H 2 O 2 -induced oxidative stress.

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