More Than One-to-Four via 2R: Evidence of an Independent Amphioxus Expansion and Two-Gene Ancestral Vertebrate State for MyoD-Related Myogenic Regulatory Factors (MRFs).

lanceolatum MRF neighborhood and human chromosomes 11 and 12 (binomial test, 11: P < 2 × 10 −3 , 12: P < 1 × 10 −2 ; Barnard’s exact test, 11: P < 1 × 10 −10 , 12: P < 2 × 10 −8 ; supplementary information 6 c – d , Supplementary Material online), whereas there was no significant association observed with chromosome 1, and only a marginally significant association with 19 in one of the tests (Barnard’s exact test, P < 0.05).

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