Comparison of the proportion of the Tes -positive lymphomas between this “Δ122-any” cohort and the homozygous Trp53 - null mice (Group 6, P = 0.0021) and between the homozygous Trp53 - mΔpro mice (Group 7, P = 0.001) were highly significant.
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Silencing of Testin expression is a frequent event in spontaneous lymphomas from Trp53-mutant mice.
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