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Combining 1,4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors.

BMC Cancer · 2020 · PMC7532092 · PMID 33008336

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a decreasing trendno p-value reported
While an evaluation of the incidence rates of CRC in the USA shows a decreasing trend between 2000 and 2014 [ 1 ] what is most worrying, is that in the last 60 years, CRC has been on the rise in the under 50 population [ 1 ].

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