In vivo glucose metabolism and glutamate levels in mGluR5 knockout mice: a multimodal neuroimaging study using [¹⁸F]FDG microPET and MRS.

However, this putative balance was absent in the mGluR5 KO mice after MK-801 challenge, where we observed a global and highly significant 25% reduction in [ 18 F]FDG uptake relative to baseline.

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