Barely Significant
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Guanidinoacetic acid deficiency: a new entity in clinical medicine?

Int J Med Sci · 2020 · PMC7532483 · PMID 33029096

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highly significantno p-value reported
The authors found a highly significant reduction in serum GAA in patients with subclinical hyperthyroidism (for 16.7% on average) and clinical hyperthyroidism (36.8%), suggesting thyroid dysfunction-driven GAA deficit that could advance the use of serum GAA as an additional sensitive marker of hyperthyroidism.

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