The contribution of inorganic phosphate is relatively low and mostly neglected, except in the case of hyperphosphatemic acidosis, which may be significant in renal failure. 5 , 11 Apart from these independent parameters, another concept has been proposed by the Stewart model—strong ion gap (SIG).
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The Impact of Intravenous Fluid Therapy on Acid-Base Status of Critically Ill Adults: A Stewart Approach-Based Perspective.
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