Identification of Essential Genes and Fluconazole Susceptibility Genes in <i>Candida glabrata</i> by Profiling <i>Hermes</i> Transposon Insertions.

The idh2 ∆ single mutant was 2.5-fold more resistant to fluconazole (IC50 = 59.4 ± 1.1 μg/mL) than wild-type BG14 (IC50 = 24.1 ± 0.9 μg/mL) and the difference was highly significant ( P = 2.8E-5, n = 3, Student’s t -test).

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