Dendritic integration in olfactory bulb granule cells upon simultaneous multispine activation: Low thresholds for nonlocal spiking activity.

Arrangement of the data relative to the transition spine number ( Fig 3D ) shows a highly significant discontinuous increase in compound uEPSP amplitudes at threshold (i.e., significantly different from linear fit to subthreshold regime, see Materials and methods ), and the concomitant increase in O/I ratios ( Fig 3E ).

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Table 1 shows that only 2 out of 12 variables correlated with Ca 2+ -spike in terms of coactivated spine numbers, whereas both D-spike and global Na + -spike initiation threshold spine numbers did not correlate significantly with any tested variable, with a weak trend for a positive correlation between spine distribution and global Na + -spike initiation ( Fig 8C ).

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