Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life.

4 f), the differences between the genotypes in center time was highly significant [genotype × time interaction, F (11,154) = 2.91, p = 0.0016].

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It should be emphasized that the change in expression of Xbp1 was trending toward significance, and the magnitude of this reduction was relatively small.

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