Barely Significant
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Effect of cyclo-oxygenase inhibitor use during checkpoint blockade immunotherapy in patients with metastatic melanoma and non-small cell lung cancer.

J Immunother Cancer · 2020 · PMC7537331 · PMID 33020239

Europe PMCDOI
1
hedged sentence
0.0590
closest p · 1.2× alpha
0.0590
boldest claim

The sentences

a favorable trendp=0.059so close (0.05 < p ≤ 0.1)
On univariate analysis, ICI+COXi was not associated with a significant increase in TTP, though there was again a favorable trend (HR 0.48, 95% CI 0.23 to 1.03; p=0.059) ( table 2 ).

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