Evaluation of the anti-inflammatory effects of synthesised tanshinone I and isotanshinone I analogues in zebrafish.

For experiments investigating resolution of neutrophilic inflammation in vivo ( Fig 6b ), TIIA 2 (25 μM) was used as the positive control compound, as this has previously been shown to exhibit highly significant pro-resolution activity in this zebrafish model of inflammation [ 63 ].

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