ROS production and mitochondrial dysfunction driven by PU.1-regulated NOX4-p22<sup>phox</sup> activation in Aβ-induced retinal pigment epithelial cell injury.

Theranostics · 2020 · PMC7546003 · PMID 33052238

Europe PMC DOI

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highly significantno p-value reported

The results are highly significant for the protection of RPE cells from Aβ-mediated oxidative stress and maintenance of the fundus microenvironment stability and thus have promising potential for therapeutic development.

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