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The Sickle Cell Disease Ontology: Enabling Collaborative Research and Co-Designing of New Planetary Health Applications.

OMICS · 2020 · PMC7549008 · PMID 33021900

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an increasing trendno p-value reported
Over 300,000 newborns are diagnosed with SCD each year globally, with an increasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.