highly significantp = 3.4 × 10 −9
In support of that notion, we compared the predicted MaxEnt and U2AF35 scores for BRCA2 and VARS2 -derived sequences corresponding to our model 3′ss (but mutated to all possible variants in the exonic part) and found a highly significant correlation between these two scores (r = 0.658 and p = 3.4 × 10 −9 for BRCA2 ; r = 0.573 and p = 7.5 × 10 −7 for VARS2 ) ( Figure S2 ; Table S2 ).