As expected, the angiogenesis score was significantly associated with Nottingham pathological grade and American Joint Committee on Cancer (AJCC) cancer staging in METABRIC ( p = 0.009 and p < 0.001) but not in TCGA cohort, although tumors with metastasis (Stage IV, N3, M1) demonstrated a notable trend to be higher score ( Figure 2 A).
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Intra-Tumoral Angiogenesis Is Associated with Inflammation, Immune Reaction and Metastatic Recurrence in Breast Cancer.
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