Catalase T-Deficient Fission Yeast Meiocytes Show Resistance to Ionizing Radiation.

The exposure to 300 Gy X irradiation induced a highly significant ( p ≤ 0.007) increase in meiocytes displaying oxidized DHE relative to control ( Figure 3 A), thus revealing IR-induced generation of superoxide and other ROS radicals in all strains tested.

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DHE loading of non-exposed meiocytes revealed ROS in ~20% of wild-type and pcl1 ∆ cells, and in ~30% of ctt1 ∆ cells, a marginally significant difference ( p = 0.049) ( Figure 3 A).

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