Tceal1 is identified as the top candidate among the negatively selected genes From the 17 highlighted genes, six genes had highly significant adjusted P -values at <0.05, among which two genes have human orthologues ( TCEAL1 and CUL9 ) ( Table 1 ).
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In vivo CRISPR/Cas9 knockout screen: TCEAL1 silencing enhances docetaxel efficacy in prostate cancer.
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