To determine a minimum concentration/time of L-ASNase for α-Syn clearance, we tested the effect of 0.1–1 IU/ml L-ASNase for 6 h and found that the inhibitory effect was stably presented and highly significant at 0.8 IU/ml ( Figure 1B ).
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L-Asparaginase Exerts Neuroprotective Effects in an SH-SY5Y-A53T Model of Parkinson's Disease by Regulating Glutamine Metabolism.
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