Clinical efficacy of chloroquine derivatives in COVID-19 infection: comparative meta-analysis between the big data and the real world.

The difference was highly significant (4/4 versus 0/17, Bilateral Mid-P exact test, p 0.00016).

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The major elements of this study are that, overall, there is an extremely significant difference between the analyses of data not collected directly by the doctors who cared for the patients and the studies carried out by the physicians who set up these studies and cared for patients, including the randomized studies.

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