We also found a non-significant U-shape dose–response effect of vitamin E (or α-tocopherol) dosage on the reduction of serum CRP in which the effect had a gradually increasing trend from 0 to 400 mg/day and then it had a decreasing trend from 400 to 1000 mg/day; such that at the dosages of ≥ 1000 mg/day, vitamin E had no significant effect on serum CRP concentrations.
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The effect of vitamin E supplementation on selected inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials.
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