a favorable trendp = 0.046
On the other hand, chemotherapy plus pembrolizumab was not formally superior to chemotherapy alone in terms of OS even if a favorable trend was seen both in CPS ≥ 1% (mOS 12.5 vs. 11.1 months, HR: 0.85, p = 0.046) and CPS ≥ 10% (mOS 12.3 vs. 10.8, HR: 0.85, p = 0.158) patients.